en سلامت روان Mental Health Original Article <div style="text-align: justify;"><strong>Background:</strong> Irritable Bowel Syndrome (IBS) is a serious syndrome, which damages people&rsquo;s psychological, communicative, social, and emotional lives. Therefore, the present study was conducted to compare integrative self-knowledge and impulsivity in patients with Irritable IBS and healthy individuals.<br> <strong>Methods:</strong> This case-control study was conducted on patients with IBS referring to gastroenterologists and healthy individuals in the city of Isfahan in 2018. The sample size included 150 patients with IBS and 150 healthy people in Isfahan selected using non-random convenient sampling method. The integrative self-knowledge and impulsivity questionnaires were applied to collect the information. After collecting the questionnaires and extracting the raw data, SPSS₂₃ software was used and t-test was run to analyze the data.<br> <strong>Results:</strong> A significant difference was observed between patients with IBS and healthy participants with regard to integrative self-knowledge and impulsivity (P-value < 0.001), so that people with IBS had lower integrative self-knowledge and higher impulsivity in comparison with the healthy individuals.<br> <strong>Conclusion:</strong> According to the findings, people with IBS had lower integrative self-knowledge and higher impulsivity due to their therapeutic and psychological involvement in the disease. So, third-wave psychological treatments such as mindfulness treatment and positivist psychotherapy are required in this area.</div> Integrative Self-Knowledge, Impulsivity, Irritable Bowel Syndrome (IBS) 340 348 http://sbrh.ssu.ac.ir/browse.php?a_code=A-10-159-2&slc_lang=en&sid=1 Saeideh Khaki Baran.khaki1991@yahoo.com 0000-0001-8929-8066 No Islamic Azad University, Isfahan Branch (Khorasgan), Isfahan, Iran. Hajar Torkan h.torkan@khuisf.ac.ir 0000-0002-0036-6964 Yes Islamic Azad University, Isfahan Branch (Khorasgan), Isfahan, Iran. Vahid Sebghatollahi sebghatollahi@gmail.com 0000-0003-0828-4711 No Department of Adult Gastroenterology, Faculty Member of Isfahan Medical University, Isfahan, Iran.